Key result
A prototype rotary biventricular support device with a mechanical passive controller maintained arterial pressures during sudden induced hemodynamic destabilization in an in vitro mock circulation loop.
A novel passively controlled rotary biventricular support device successfully maintained arterial pressures during hemodynamic destabilization in an in vitro mock circulation loop.
No immediate clinical implications; leaves open in vivo performance of passively controlled biventricular support.
Clinical studies have reported the balancing of pump outputs to be a serious control issue for rotary biventricular support (BiVS) systems. Poor reliability of long-term, blood immersed pressure sensors encouraged the development of a new control strategy to improve their viability. A rotary BiVS device was designed and constructed with a mechanical passive controller to autoregulate pump outputs to emulate the native baroreceptor response. In vitro testing in a dual circuit, hydraulic mock circulation loop showed that the prototype was able to maintain arterial pressures when subjected to sudden induced hemodynamic destabilization. However, inlet suction was observed when sudden simulated hypertension briefly reduced venous return to the cannulated ventricle. The results have encouraged further development of the device as a means to create an inherently stable, fully passive biventricular support device.
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Gaddum et al. (2010) studied this question. Rotary biventricular support (BiVS) device with a mechanical passive controller was evaluated on Ability to maintain arterial pressures during sudden induced hemodynamic destabilization. A prototype rotary biventricular support device with a mechanical passive controller maintained arterial pressures during sudden induced hemodynamic destabilization in an in vitro mock circulation loop.
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