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January 1, 2018Journal of Clinical and Preventive CardiologyOpen Access

Comparative analysis of acute coronary syndrome in the elderly and the young: A hospital-based observational study

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Key result

Younger patients (<60 years) with acute coronary syndrome had significantly higher Killip class, heart failure, shock, and mortality compared to elderly patients (>60 years) (P<0.05).

Why the study?

Do risk factors, clinical presentation, and in-hospital outcomes of acute coronary syndrome differ between elderly (>60 years) and younger (<60 years) patients?

Population

311 patients hospitalized with acute coronary syndromes over a 12-month period, categorized as >60 years and…

Comparison

Age >60 years (elderly cohort) vs Age <60 years (younger cohort)

Design

Cross-sectional

Follow-up

in-hospital

Authors

SASohaib AhmadACAbhikant ChughARAnurag Rawat

Discussion

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Member takes

Overview

Younger ACS patients may warrant closer monitoring for complications; hypothesis-generating and requires prospective confirmation before guiding practice.

Study Design

Type

Cross-Sectional (n=311)

Structured PICO

Do risk factors, clinical presentation, and in-hospital outcomes of acute coronary syndrome differ between elderly (>60 years) and younger (<60 years) patients?

P
Population
311 patients hospitalized with acute coronary syndrome over a 12-month period, categorized into elderly (>60 years) and younger (<60 years) groups.
E
Exposure
Age >60 years (elderly cohort)
C
Comparator
Age <60 years (younger cohort)
O
Outcome
Risk factors, clinical presentation, echocardiographic and angiographic findings, complications, and in-hospital outcomes (including mortality)hard clinical

Main Result

p-value: p=<0.05

This observational study highlights significant differences in the risk factor profile and clinical presentation of ACS between elderly and younger patients, with the younger cohort presenting with higher rates of heart failure, shock, and in-hospital mortality.

Cite This Study

Ahmad et al. (2018) conducted a cross-sectional in Acute coronary syndrome (n=311). Younger age (<60 years) vs. Elderly age (>60 years) was evaluated on Mortality, Killip class, heart failure, and shock (p=<0.05). Younger patients (<60 years) with acute coronary syndrome had significantly higher Killip class, heart failure, shock, and mortality compared to elderly patients (>60 years) (P<0.05).

synapsesocial.com/papers/6a97418e8bc05dff469bb55bhttps://doi.org/10.4103/jcpc.jcpc_4_18
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adverse Psychological and Coronary Risk Profiles in Young Patients With Coronary Artery Disease and Benefits of Formal Cardiac Rehabilitation2006 · 182 citations
  2. 2Hospital and 4‐Year Mortality Predictors in Patients With Acute Pulmonary Edema With and Without Coronary Artery Disease2016 · 16 citations
  3. 3ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)2011 · 3,095 citations
  4. 4Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart Association2018 · 7,258 citations