Key result
Younger patients (<60 years) with acute coronary syndrome had higher Killip class, heart failure, shock, and mortality compared to elderly patients (>60 years).
Why the study?
Do risk factors, clinical presentation, and in-hospital outcomes of acute coronary syndrome differ between elderly (>60 years) and younger (<60 years) patients?
Cross-Sectional (n=311)
Do risk factors, clinical presentation, and in-hospital outcomes of acute coronary syndrome differ between elderly (>60 years) and younger (<60 years) patients?
Answers are grounded in this paper and cite their sources.
This observational study highlights significant differences in the risk factor profile and clinical presentation of ACS between elderly and younger patients, with the younger cohort presenting with higher rates of heart failure, shock, and in-hospital mortality.
Background: The high prevalence of acute coronary syndromes (ACS) and the imminent transition of a proportion of the population into the geriatric age group are issues vital to the health-care delivery system. We wished to compare the risk factors, clinical presentation, echocardiographic and angiographic findings, complications, and in-hospital outcomes of ACS in the elderly and the younger population and identify the predictors of mortality in the elderly. Materials and Methods: This observational cross-sectional study was performed on patients hospitalized with ACS over a 12-month period. Demographic, clinical, and laboratory data of all included patients were analyzed after categorizing them as Groups I (>60 years; n = 188) and II (<60 years; n = 123). Results: Congestive heart failure (n = 64; 20.6%), shock (n = 19; 6.1%), and arrhythmias (n = 9; 2.9%) were observed at presentation in the 311 patients studied. Intervention was not undertaken in 18/311 (5.8%) either due to poor general condition or refusal by the patients' attendants. The risk factors significantly associated (P < 0.05) in Group II included male gender, tobacco and alcohol use, central obesity, dyslipidemia, and a positive family history of coronary artery disease (CAD). Group II had significantly higher (P < 0.05) Killip class, heart failure, and shock at presentation and mortality. Conclusion: The risk factors of CAD differ in the elderly; also they are predisposed to adverse outcome as compared to the younger people. Mortality among the elderly is significantly higher in those with arrhythmias, shock, low diastolic blood pressure, and/or congestive heart failure with advanced Killip class.
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Ahmad et al. (2018) conducted a cross-sectional in Acute coronary syndrome (n=311). Younger age (<60 years) vs. Elderly age (>60 years) was evaluated on Mortality, Killip class, heart failure, and shock (p=<0.05). Younger patients (<60 years) with acute coronary syndrome had higher Killip class, heart failure, shock, and mortality compared to elderly patients (>60 years).
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