The clinical and coronary angiographic profile of 601 older adult patients with acute coronary syndrome treated at a tertiary hospital in North India and complications of percutaneous coronary intervention with the 30-day mortality
Why the study?
The study was conducted to identify the clinical and coronary angiographic profile of older adult patients with acute coronary syndrome and assess complications of percutaneous coronary intervention and 30-day mortality.
What are the clinical and angiographic profiles, PCI complications, and 30-day mortality rates in older adult patients with ACS undergoing coronary angiography?
Population
601 older adult patients with ACS who underwent CAG at a tertiary hospital in North India
Comparison
Patients aged 60–70 years vs >70 years
Design
Prospective observational study
Follow-up
30 days
Authors
Discussion
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Member takes
Implication
Age >70 years linked to higher 30-day mortality after PCI for ACS; leaves open optimal management strategies in this subgroup.
Structured PICO
What are the clinical and angiographic profiles, PCI complications, and 30-day mortality rates in older adult patients with ACS undergoing coronary angiography?
P
Population
601 older adult patients (≥60 years) with acute coronary syndrome (ACS) who underwent coronary angiography (CAG) over 2 years (2017–2019), mean age 77 ± 17 years, 80.9% male, at a tertiary hospital in North India.
I
Intervention
Coronary angiography (CAG) and percutaneous coronary intervention (PCI)
O
Outcome
Clinical and coronary angiographic profile, complications of PCI (contrast-induced nephropathy, intracerebral hemorrhage), and 30-day mortalityhard clinical
In older adults with ACS, coronary angiography and PCI are associated with low rates of procedural complications, though 30-day mortality is significantly higher in patients over 70 years of age.
Cite This Study
Shabir et al. (2020) studied this question.