Key result
HoBi-like pestivirus infection in cattle causes significant reproductive disorders, including abortion, stillbirths, and the birth of persistently infected calves, similar to other bovine pestiviruses.
Why the study?
HoBi-like pestivirus causes diverse clinical disease and economic losses in cattle mainly from reproductive failures, warranting an updated review of its impact on cattle reproduction.
HoBi-like pestivirus is an emerging pathogen that causes severe reproductive disorders in cattle, highlighting the need for updated diagnostic tools and vaccine efficacy evaluations.
HoBiPeV warrants inclusion in ruminant reproductive failure differentials; leaves open needs for updated diagnostics and vaccine evaluation.
HoBi-like pestivirus (HoBiPeV) is an emerging group of pestiviruses that has been detected in cattle and other ruminants in South America, Europe, and Asia. Analogous to other bovine pestiviruses, namely bovine viral diarrhea (BVDV) 1 and 2, HoBiPeV is able to cause a variety of clinical forms that range from asymptomatic infections to fatal disease, having a great impact on cattle productions and causing substantial economic losses, mainly as a consequence of the occurrence of reproductive failures. The manuscript aims to provide an updated review of the currently available literature about the impact of HoBiPeV infection on cattle reproduction. The reproductive disorders observed in cattle due to natural and experimental infections caused by this virus are reported along with the few available in-vitro studies involving the reproductive tract. HoBiPeV should be considered among the bovine pathogens that impact on reproduction, but there is a need for more specific and sensitive diagnostic methods, while the cross-protection elicited by commercially available BVDV vaccines should be better investigated.
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Nicola Decaro (2020) conducted a review in HoBi-like pestivirus (HoBiPeV) infection and reproductive disorders. HoBi-like pestivirus (HoBiPeV) infection was evaluated. HoBi-like pestivirus infection in cattle causes significant reproductive disorders, including abortion, stillbirths, and the birth of persistently infected calves, similar to other bovine pestiviruses.
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