Key result
Magnetic resonance imaging using an interleaved gradient echo pulse sequence showed a close correlation with indicator dilution-derived cardiac output (r = 0.96, p < 0.001).
Why the study?
Does magnetic resonance imaging using an interleaved gradient echo pulse sequence accurately determine cardiac output compared to traditional methods in normal volunteers and patients?
Observational (n=13)
Does magnetic resonance imaging using an interleaved gradient echo pulse sequence accurately determine cardiac output compared to traditional methods in normal volunteers and patients?
Magnetic resonance imaging using an interleaved gradient echo pulse sequence is a reliable method for quantitative in vivo flow measurements of cardiac output.
Answers are grounded in this paper and cite their sources.
Supports MRI for noninvasive cardiac output assessment; leaves open prospective validation in larger cohorts.
Quantitative flow measurements to determine forward flow in the ascending aorta were performed in 7 normal volunteers and in 6 patients by magnetic resonance imaging using an interleaved gradient echo pulse sequence. Cardiac output was determined simultaneously by a classical indicator dilution technique in the normals. In the patients, left- and right-ventricular stroke volumes were determined immediately before the flow measurement by a traditional spin echo multislice technique. There was a close correlation between aortic forward flow- and indicator dilution-derived cardiac output (r = 0.96, p < 0.001 ). Moreover, there was good agreement between aortic forward flow and left-ventricular stroke volume (r = 0.95, p < 0.01) and between aortic forward flow and right-ventricular stroke volume (r = 0.98, p < 0.001). The results indicate that the flow sequence is a reliable method for quantitative in vivo flow measurements.
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Møgelvang et al. (2017) reported an observational. Magnetic resonance imaging (interleaved gradient echo pulse sequence) vs. Indicator dilution technique and spin echo multislice technique was evaluated on Correlation between aortic forward flow and indicator dilution-derived cardiac output (r = 0.96, p=<0.001). Magnetic resonance imaging using an interleaved gradient echo pulse sequence showed a close correlation with indicator dilution-derived cardiac output (r = 0.96, p < 0.001).
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