Key result
Diabetic ketoacidosis with hyperkalaemia uncovered a typical Brugada syndrome ECG, leading to a confirmed familial diagnosis after provocation testing.
Case Report (n=1)
Metabolic derangements such as hyperkalaemia during diabetic ketoacidosis can unmask Brugada syndrome, warranting careful ECG monitoring and family screening to prevent sudden death.
Hyperkalaemia in DKA may unmask Brugada ECG; leaves open whether monitoring or family screening improves outcomes.
We describe a case of diabetic ketoacidosis with concomitant hyperkalaemia that uncovered a typical Brugada syndrome electrocardiogram (ECG). Further provocation testing in the patient and his son confirmed familial Brugada syndrome. Diabetic ketoacidosis with hyperkalaemia may uncover an inheritable arrhythmia syndrome that may put the patient and his/her next of kin at risk for a sudden death, irrespective of diabetes mellitus.
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Postema et al. (2011) conducted a case report in Diabetic ketoacidosis with hyperkalaemia and Brugada syndrome (n=1). Hyperkalaemic diabetic ketoacidosis was evaluated on Uncovering of typical Brugada syndrome ECG. Diabetic ketoacidosis with hyperkalaemia uncovered a typical Brugada syndrome ECG, leading to a confirmed familial diagnosis after provocation testing.
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