Key result
The intergenic region IRES from the Dicistroviridae family of viruses serves as an important model for understanding IRES-dependent translation and fundamental properties of translation.
This review highlights the intergenic region IRES from the Dicistroviridae family as a model for understanding IRES-dependent translation.
To replicate, all viruses depend entirely on the enslavement of host cell ribosomes for their own advantage. To this end, viruses have evolved a multitude of translational strategies to usurp the ribosome. RNA-based structures known as internal ribosome entry sites (IRESs) are among the most notable mechanisms employed by viruses to seize host ribosomes. In this article, we spotlight the intergenic region IRES from the Dicistroviridae family of viruses and its importance as a model for IRES-dependent translation and in understanding fundamental properties of translation.
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Kerr et al. (2016) conducted a review in Viral translation mechanisms. The intergenic region IRES from the Dicistroviridae family of viruses serves as an important model for understanding IRES-dependent translation and fundamental properties of translation.
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