Key result
Experimental infection of mongooses with encephalomyocarditis virus resulted in high mortality (10 of 14 animals) and fulminating myocarditis, with the highest virus titers found in the myocardium.
Population
Mongooses of 2 species live-trapped in and near Entebbe, Uganda. Palm civets, genets, and an African grivet…
Design
Preclinical
Follow-up
2.5 to 6 days
Authors
Loading...
May implicate mongooses as EMCV reservoirs; hypothesis-generating for zoonotic myocarditis surveillance.
Experimental EMC virus infection in mongooses causes fulminating myocarditis with high viral titers in the heart, highlighting their potential role as natural reservoirs.
Kilham et al. (1956) studied Encephalomyocarditis (EMC) virus infection (n=14). Encephalomyocarditis (EMC) virus was evaluated on Mortality and tissue virus titers. Experimental infection of mongooses with encephalomyocarditis virus resulted in high mortality (10 of 14 animals) and fulminating myocarditis, with the highest virus titers found in the myocardium.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: