Key result
A review of the literature on idiopathic hypertrophy of the heart in infants and young children revealed that fully half of reported cases were secondary to myocardial disease or other etiologic factors.
Population
Infants and young children with dilatation and hypertrophy of the heart (so-called idiopathic hypertrophy)
Design
Review
Authors
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Challenges idiopathic label in half of pediatric hypertrophy cases; leaves open systematic etiologic evaluation in modern cohorts.
Highlights that many historical cases of 'idiopathic' cardiac hypertrophy in infants and children have identifiable underlying myocardial disease or other etiologies upon postmortem examination.
Markus Kügel (1933) conducted a review in Idiopathic hypertrophy of the heart. A review of the literature on idiopathic hypertrophy of the heart in infants and young children revealed that fully half of reported cases were secondary to myocardial disease or other etiologic factors.
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