Key result
Among 34 literature cases of so-called idiopathic enlargement of the heart, only 17 were considered true idiopathic hypertrophy after excluding those with underlying pathologic abnormalities.
Population
34 cases from the literature reported as idiopathic enlargement of the heart in infancy and childhood with…
Design
Review
Authors
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Many historical "idiopathic" pediatric cardiomegaly cases had overlooked causes; leaves open true prevalence and modern diagnostic criteria.
A historical review of literature cases reveals that many instances of so-called idiopathic heart enlargement in infants and children had underlying pathologic explanations, leaving only a subset as truly idiopathic.
E. GORDON STOLOFF (1928) conducted a review in Idiopathic enlargement of the heart (n=34). Among 34 literature cases of so-called idiopathic enlargement of the heart, only 17 were considered true idiopathic hypertrophy after excluding those with underlying pathologic abnormalities.
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