Key result
A comprehensive management program for heart failure reduced hospital admissions by 87.2% (from a mean of 1.05 to 0.08 admissions per patient) at 6 months (P<0.0001).
Why the study?
Does a comprehensive management program reduce hospital readmissions in patients with symptomatic HFrEF?
Does a comprehensive management program reduce hospital readmissions in patients with symptomatic HFrEF?
Effect estimate: 87.2% reduction
Absolute Event Rate: 0.08% vs 1.05%
p-value: p=<0.0001
A comprehensive management program significantly reduces hospital readmissions and improves quality of life, exercise capacity, and guideline-directed medical therapy dosing in patients with HFrEF.
May support HF programs to cut admissions; leaves open confirmation in randomized HFrEF trials.
AIMS: Congestive heart failure (CHF) is associated with a high readmission rate after diagnosis. We assessed the ability of a comprehensive management program (CMP) for CHF to reduce readmissions with secondary endpoints of improving quality of life, exercise capacity and targeted drug doses. METHODS AND RESULTS: Patients (pts) with: New York Heart Association Class (NYHA) III or IV CHF; left ventricular ejection fraction <40%; and stable outpatient therapy were assigned to a CMP of cardiology assessment intensive education and referral to a tailored exercise program. Forty-two pts (35 M, 7 F, mean age 54 years, S.D. 12 years) were enrolled. Two pts were transplanted, two died during follow-up and two were lost to follow-up. Hospital admissions were reduced by 87.2%, (mean 1.05, S.D. 0.98, admissions per pt to mean 0.08, S.D. 0.28, admissions per pt at 6-month follow-up; P<0.0001). ACE-inhibitor dose increased by 42% (P<0.0008) and beta-blocker dose increased by 61% (P<0.0001). NYHA Class, 6-min walk and quality of life scores all improved significantly (P<0.0001). CONCLUSION: A CMP improves QOL and exercise capacity as well as substantially reducing hospital admissions in CHF pts. This study validates the benefit of intensive outpatient care of CHF.
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Holst et al. (2001) studied Congestive heart failure (CHF) (n=42). Comprehensive management program (CMP) vs. Pre-intervention baseline was evaluated on Hospital admissions (87.2% reduction, p=<0.0001). A comprehensive management program for heart failure reduced hospital admissions by 87.2% (from a mean of 1.05 to 0.08 admissions per patient) at 6 months (P<0.0001).
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