Key result
Intravenous enalaprilat infusion caused significant but short-lasting decreases in pulmonary artery occlusion pressure (P=0.007) and mean arterial pressure (P=0.003).
Why the study?
Does intravenous enalaprilat improve hemodynamics and relieve pulmonary congestion in critically ill patients with intractable acute heart failure after myocardial infarction?
Population
8 critically ill patients with intractable acute heart failure after acute myocardial infarction.
Comparison
Intravenous enalaprilat infused at a rate of 1… vs Baseline measurements.
Design
Case_series
Follow-up
2 hours
Authors
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May transiently relieve pulmonary congestion in refractory post-MI HF; case report leaves open efficacy and safety in trials.
Does intravenous enalaprilat improve hemodynamics and relieve pulmonary congestion in critically ill patients with intractable acute heart failure after myocardial infarction?
p-value: p=0.007
Intravenous enalaprilat provides transient relief of pulmonary congestion in patients with intractable heart failure post-myocardial infarction without compromising cardiac output or systemic oxygenation.
Tohmo et al. (1994) studied intractable acute heart failure after acute myocardial infarction (n=8). Enalaprilat vs. Baseline was evaluated on Pulmonary artery occlusion pressure (p=0.007). Intravenous enalaprilat infusion caused significant but short-lasting decreases in pulmonary artery occlusion pressure (P=0.007) and mean arterial pressure (P=0.003).
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