Key result
Hypocalcemia was associated with significantly increased QTc interval, Tp-e interval, and Tp-e/QTc ratio compared to normocalcemic controls.
Why the study?
Studies have evaluated QT and QTc intervals in patients with hypocalcemia, but none have assessed Tp-e interval or Tp-e/QT and Tp-e/QTc ratios to evaluate ventricular repolarization and arrhythmia risk.
Does hypocalcemia increase Tp-e interval and Tp-e/QTc ratio compared to normocalcemia?
Case-Control (n=58)
No
Does hypocalcemia increase Tp-e interval and Tp-e/QTc ratio compared to normocalcemia?
Absolute Event Rate: 128.38% vs 77.38%
p-value: p=<0.001
Hypocalcemia is associated with significantly prolonged Tp-e intervals and increased Tp-e/QTc ratios, suggesting these ECG parameters may be useful for monitoring ventricular arrhythmia risk in these patients.
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Avcı et al. (2021) conducted a case-control in Hypocalcemia (n=58). Hypocalcemia vs. Normocalcemia was evaluated on Tp-e interval (ms) (p=<0.001). Hypocalcemia was associated with significantly increased QTc interval, Tp-e interval, and Tp-e/QTc ratio compared to normocalcemic controls.
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