Key result
Grade I hypertension was associated with a 3.4-fold greater increase in mean carotid intima-media thickness over 5 years compared to normotensive controls (P<0.01).
Why the study?
Does grade I hypertension (white-coat or sustained) increase the rate of carotid intima-media thickness progression compared to normotension in young adults?
Cohort (n=94)
Does grade I hypertension (white-coat or sustained) increase the rate of carotid intima-media thickness progression compared to normotension in young adults?
p-value: p=<0.01
Grade I hypertension, whether white-coat or sustained, is associated with a significantly faster progression of carotid intima-media thickness compared to normotension in young adults.
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May identify higher vascular risk in young adults; leaves open whether early BP control slows progression.
Puato et al. (2008) conducted a cohort in Grade I hypertension (n=94). Grade I hypertension vs. Normotensive control subjects was evaluated on Increase in carotid intima-media thickness (IMT) (p=<0.01). Grade I hypertension was associated with a 3.4-fold greater increase in mean carotid intima-media thickness over 5 years compared to normotensive controls (P<0.01).
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