Key result
The highest versus lowest quartile of serum uric acid was associated with increased odds of metabolic syndrome in men (OR 3.06), premenopausal (OR 3.42), and postmenopausal women (OR 1.87).
Why the study?
Is higher serum uric acid associated with an increased risk of metabolic syndrome in men and women?
Cross-Sectional (n=1,834)
Is higher serum uric acid associated with an increased risk of metabolic syndrome in men and women?
Odds Ratio: 3.06 (95% CI 1.64–5.7)
p-value: p=<0.001
Higher serum uric acid levels are independently associated with a greater likelihood of metabolic syndrome across men and women, with a particularly strong association in premenopausal women.
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May inform risk stratification but should not change practice; leaves open causal confirmation in prospective studies.
Li et al. (2014) conducted a cross-sectional in Metabolic syndrome (n=1,834). Highest quartile of serum uric acid vs. Lowest quartile of serum uric acid was evaluated on Presence of metabolic syndrome (OR 3.06, 95% CI 1.64-5.70, p=<0.001). The highest versus lowest quartile of serum uric acid was associated with increased odds of metabolic syndrome in men (OR 3.06), premenopausal (OR 3.42), and postmenopausal women (OR 1.87).
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