Why the study?
Does disopyramide, procainamide, or digoxin improve arrhythmia control in patients with paroxysmal supraventricular tachycardia compared to placebo?
Population
10 patients with an established diagnosis of paroxysmal supraventricular tachycardia
Comparison
Disopyramide, procainamide, and digoxin… vs Placebo
Design
RCT, random sequence, double-blind
Follow-up
two-week periods per treatment
Authors
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Disopyramide may warrant consideration for paroxysmal SVT prophylaxis; leaves open efficacy ranking pending larger powered trials.
Does disopyramide, procainamide, or digoxin improve arrhythmia control in patients with paroxysmal supraventricular tachycardia compared to placebo?
In a small crossover trial of patients with paroxysmal SVT, disopyramide appeared more effective than procainamide or digoxin for arrhythmia prophylaxis, though the study lacked statistical power.
Craig et al. (1979) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: