Key result
The PRV MACELISA demonstrated a specificity of 95% for detecting PRV-specific IgM antibodies in swine sera, enabling rapid serodiagnosis of recent infection.
Population
Sera from young swine
Comparison
Immunoglobulin M antibody capture enzyme-linked… vs Indirect IgM enzyme-linked immunosorbent assay
Design
Preclinical
Follow-up
21 days
Authors
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Hypothesis-generating for PRV serodiagnosis in swine; prospective validation required before veterinary adoption.
The PRV MACELISA is a specific and sensitive assay useful for the rapid serodiagnosis of recent pseudorabies virus infection in swine.
McCaw et al. (1992) studied Pseudorabies virus (PRV) infection. PRV MACELISA vs. indirect IgM ELISA was evaluated on Specificity. The PRV MACELISA demonstrated a specificity of 95% for detecting PRV-specific IgM antibodies in swine sera, enabling rapid serodiagnosis of recent infection.
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