Key result
A new catheter-based technique enables the collection of venous blood from the canine femur to measure blood flow and the net flux of plasma constituents in vivo.
Population
Canine femur model (acute and chronic, unanesthetized preparations)
Design
Preclinical
Authors
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Enables preclinical bone perfusion studies in canines; leaves open validation and translation to human skeletal blood flow assessment.
This study describes a novel in vivo technique for isolating and measuring venous efflux from the canine femur to assess bone metabolism and blood flow.
Post et al. (1964) studied this question. New technique for collection of venous blood from the canine femur was evaluated on Rate of blood flow and net flux of plasma constituents across the intact canine femur. A new catheter-based technique enables the collection of venous blood from the canine femur to measure blood flow and the net flux of plasma constituents in vivo.
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