Key result
Blood flow values estimated using 85 Sr-labelled microspheres in rabbits were 0.068 g/min/g for quadriceps tendon, 0.250 for bone marrow, and 0.010 for cortical bone.
Population
10 anesthetized adult rabbits
Design
Preclinical
Authors
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Rabbit perfusion data validate microsphere technique for minute bone/tendon regions; leaves open human translation.
Radioactive microspheres can be used to measure blood flow in minute tissue regions such as cortical bone and bone marrow in a rabbit model.
Lunde et al. (1970) studied this question. 85 Sr-labelled plastic microspheres was evaluated on Blood flow values in specific tissues (g/min x g tissue). Blood flow values estimated using 85 Sr-labelled microspheres in rabbits were 0.068 g/min/g for quadriceps tendon, 0.250 for bone marrow, and 0.010 for cortical bone.
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