Key result
The radioactive microsphere method can be conveniently used for hemodynamic studies in the rat, with the abdominal aorta being the preferred site for the reference catheter.
Answers are grounded in this paper and cite their sources.
The radioactive microsphere technique was applied to determine simultaneous cardiac output and flow distribution in the rat. Left ventricular injections of large numbers of microspheres were given, without significant adverse effects, allowing determination of flow to organs and tissues with low perfusion rates. In order to determine coronary blood flow it was necessary to excise the inner lining of the left ventricle, thus eliminating activity from deposits of microspheres. Cardiac output determination showed less variation with the sampling catheter in the abdominal aorta than in the femoral artery. It is concluded that the microsphere method can be conveniently used for hemodynamic studies in the rat, and that the abdominal aorta is the preferred site for the placement of the reference catheter in the rat.
No takes yet. Share an insight, caveat, or question.
Idvall et al. (2008) studied this question. Radioactive microsphere technique was evaluated on Cardiac output and flow distribution. The radioactive microsphere method can be conveniently used for hemodynamic studies in the rat, with the abdominal aorta being the preferred site for the reference catheter.
Synapse has enriched 10 related papers. Consider them for comparative context: