Key result
Calcium channel blockers prescribed for hypertensive patients were associated with an increased risk of myocardial infarction compared with diuretics alone (RR 1.6; 95% CI 1.1 to 2.3).
Why the study?
Do calcium channel blockers increase the risk of myocardial infarction in hypertensive patients compared to diuretics alone?
Population
Hypertensive patients enrolled in the Group Health Cooperative of Puget Sound
Comparison
Calcium channel blockers vs Diuretics alone
Design
Editorial
Authors
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This editorial highlights a case-control study suggesting an association between calcium channel blocker use and increased risk of myocardial infarction in hypertensive patients, emphasizing the need for definitive testing.
Case-Control
Do calcium channel blockers increase the risk of myocardial infarction in hypertensive patients compared to diuretics alone?
Relative Risk: 1.6 (95% CI 1.1–2.3)
This editorial highlights a case-control study suggesting an association between calcium channel blocker use and increased risk of myocardial infarction in hypertensive patients, emphasizing the need for definitive testing.
J. E. Buring (1995) conducted a case-control in Hypertension. Calcium channel blockers vs. Diuretics alone was evaluated on Myocardial infarction (RR 1.6, 95% CI 1.1 to 2.3). Calcium channel blockers prescribed for hypertensive patients were associated with an increased risk of myocardial infarction compared with diuretics alone (RR 1.6; 95% CI 1.1 to 2.3).
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