Key result
Propofol and thiopentone resulted in a peak cardiovascular response occurring on average 31 seconds and 32 seconds, respectively, after the start of laryngoscopy and intubation.
Why the study?
Does propofol compared to thiopentone alter the timing of peak pressor response following endotracheal intubation in ASA 1 or 2 patients?
RCT (n=30)
randomised
Does propofol compared to thiopentone alter the timing of peak pressor response following endotracheal intubation in ASA 1 or 2 patients?
Absolute Event Rate: 31% vs 32%
Slow arm-cuff-based arterial pressure measurement techniques may miss important hypertensive episodes during laryngoscopy and endotracheal intubation, as peak responses occur rapidly (around 31-32 seconds).
No takes yet. Share an insight, caveat, or question.
Peak pressor responses occur ~31-32 seconds after intubation with either agent; challenges adequacy of intermittent cuff BP monitoring during induction.
Hickey et al. (1992) conducted an RCT in Patients undergoing laryngoscopy and endotracheal intubation (n=30). Propofol vs. Thiopentone 4.5 mg.kg-1 was evaluated on Timing of the peak cardiovascular response following laryngoscopy and endotracheal intubation. Propofol and thiopentone resulted in a peak cardiovascular response occurring on average 31 seconds and 32 seconds, respectively, after the start of laryngoscopy and intubation.
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