Key result
Treatment with Levosimendan improved left ventricular dysfunction, increased cardiac index, decreased pulmonary vascular resistance, and reduced the frequency and extent of pulmonary hypertension crises.
Why the study?
Does Levosimendan improve cardiac function and reduce pulmonary hypertension crises in an infant with myocardial infarction and refractory pulmonary hypertension?
Population
1 infant with myocardial infarction due to congenital stenosis of the left coronary artery with consecutive…
Design
Case_report
Authors
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Hypothesis-generating for levosimendan in infants with MI and refractory PH; controlled trials needed before adoption.
Case Report (n=1)
Does Levosimendan improve cardiac function and reduce pulmonary hypertension crises in an infant with myocardial infarction and refractory pulmonary hypertension?
Levosimendan may serve as an effective long-term inotropic agent and pulmonary vasodilator in infants with depressed cardiac function and refractory pulmonary hypertension.
Yc et al. (2004) conducted a case report in Myocardial infarction with refractory pulmonary hypertension (n=1). Levosimendan vs. Catecholamines and inhaled nitric oxide (prior failed therapies) was evaluated on Left ventricular dysfunction, cardiac index, pulmonary vascular resistance, and pulmonary hypertension crises. Treatment with Levosimendan improved left ventricular dysfunction, increased cardiac index, decreased pulmonary vascular resistance, and reduced the frequency and extent of pulmonary hypertension crises.
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