Key result
Levosimendan improves symptoms and subpulmonary LV systolic function in ccTGA.
Why the study?
The effects of levosimendan on acute decompensated heart failure in patients with congenitally corrected transposition of the great arteries are not well characterized.
Population
Single patient with congenitally corrected transposition of the great arteries and acute decompensated heart failure
Comparison
Levosimendan treatment effects observed without comparator
Design
Case report
Authors
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May support levosimendan in select ccTGA cases; hypothesis-generating and requires prospective trials before practice change.
Case Report (n=1)
Lilian Mantziari (2012) conducted a case report in Acute decompensated heart failure with congenitally corrected transposition of great arteries (n=1). Levosimendan was evaluated on Symptomatic and functional improvement, and ventricular function. Levosimendan infusion in a patient with congenitally corrected transposition of great arteries resulted in symptomatic improvement and improved subpulmonary left ventricular systolic function.
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