Key result
Patients with mild abortive poliomyelitis demonstrated an increase in neutralizing antibodies against the virus in convalescent serum samples obtained within 4 weeks of acute illness.
Demonstrates an increase in neutralizing antibodies in convalescent sera from mild cases of abortive poliomyelitis.
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May support early seroconversion in mild abortive poliomyelitis; leaves open protective role and vaccine implications.
The neutralizing antibody content for poliomyelitis virus has been tested with both a human and a passage strain of the virus in serial samples of sera from five mild cases of abortive poliomyelitis, and an increase in this antibody content has been demonstrated in convalescent samples obtained within 4 weeks of the acute illness.
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Trask et al. (1933) studied this question. Patients with mild abortive poliomyelitis demonstrated an increase in neutralizing antibodies against the virus in convalescent serum samples obtained within 4 weeks of acute illness.
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