Key result
Anti-inflammatory drugs, particularly NSAIDs and coxibs, increase cardiovascular risk, while the evidence for glucocorticoids inducing cardiovascular events remains less clear.
Why the study?
Do anti-inflammatory drugs (NSAIDs, coxibs, and glucocorticoids) increase the risk of cardiovascular events?
Population
Patients prescribed anti-inflammatory drugs for musculoskeletal conditions, such as osteoarthritis and…
Design
Review
Authors
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Supports CV risk assessment before NSAID or coxib use; leaves glucocorticoid CV effects unresolved.
Do anti-inflammatory drugs (NSAIDs, coxibs, and glucocorticoids) increase the risk of cardiovascular events?
NSAIDs, particularly COX-2 inhibitors, are associated with increased cardiovascular risk, highlighting the importance of cardiovascular risk assessment before prescribing these medications.
Roubille et al. (2013) conducted a review in Musculoskeletal conditions, osteoarthritis, and inflammatory rheumatic diseases. Anti-inflammatory drugs (NSAIDs, coxibs, and glucocorticoids) was evaluated on Cardiovascular risk and events. Anti-inflammatory drugs, particularly NSAIDs and coxibs, increase cardiovascular risk, while the evidence for glucocorticoids inducing cardiovascular events remains less clear.
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