Key result
In heart failure patients undergoing catheter ablation, recurrent atrial fibrillation strongly predicted stroke or death (HR 8.33; 95% CI 1.86-37.7; P=0.001).
Why the study?
Does maintaining sinus rhythm after catheter ablation of atrial fibrillation improve heart failure status and reduce long-term rates of stroke and death in patients with heart failure?
Population
1273 consecutive patients undergoing catheter ablation of atrial fibrillation, including 171 with heart…
Comparison
Catheter ablation of atrial fibrillation vs Patients without heart failure and patients with…
Design
Cohort
Follow-up
median 3.1 years (IQR 2.0-4.3)
Authors
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AF recurrence after ablation strongly predicts stroke/death in HF patients; observational data leave open whether sinus rhythm maintenance improves hard outcomes.
Cohort (n=1,273)
Yes
Does maintaining sinus rhythm after catheter ablation of atrial fibrillation improve heart failure status and reduce long-term rates of stroke and death in patients with heart failure?
Hazard Ratio: 8.33 (95% CI 1.86–37.7)
p-value: p=0.001
In patients with heart failure undergoing atrial fibrillation ablation, maintaining sinus rhythm is associated with improved symptoms, better left ventricular function, and a significantly lower risk of stroke and death.
Ullah et al. (2016) conducted a cohort in Atrial fibrillation with heart failure (n=1,273). Recurrent atrial fibrillation vs. Maintained sinus rhythm was evaluated on stroke or death (HR 8.33, 95% CI 1.86-37.7, p=0.001). In heart failure patients undergoing catheter ablation, recurrent atrial fibrillation strongly predicted stroke or death (HR 8.33; 95% CI 1.86-37.7; P=0.001).
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