This review discusses the mechanisms, prognostic implications, and echocardiographic quantification of functional mitral regurgitation in heart failure patients undergoing cardiac resynchronization therapy.
Synthesizes FMR mechanisms and quantification in CRT recipients; leaves open prospective trials on management.
Cardiac resynchronization therapy (CRT) is a promising new therapy for symptomatic patients with systolic heart failure despite optimized medical therapy and mechanical dyssynchrony in the setting of intraventricular conduction delay. The contractile discoordination may also involve the papillary muscles and result in functional mitral regurgitation which can be reduced by CRT. This review will discuss mechanisms and prognostic implications of mitral regurgitation, methods how to quantitate this valvular heart disease, and the role of mitral regurgitation in patients with mechanical dyssynchrony.
No takes yet. Share an insight, caveat, or question.
R BRANDT (2004) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: