Exercise regulates cardiac metabolism: Sex does matter
Key result
Exercise induces dynamic changes in cardiac substrate metabolism, but the specific effects of acute and chronic exercise on metabolic pathway regulation remain unclear due to inconsistent findings.
Why the study?
The effects of acute exercise and chronic exercise training on cellular metabolism and metabolic pathway regulation remain unclear, with inconsistent findings regarding substrate oxidation in exercise-adapted hearts.
Design
Review
Authors
Discussion
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Member takes
Implication
Sex differences in exercise-induced cardiac metabolic remodeling require targeted study; leaves open precise effects of acute versus chronic exercise on pathway regulation.
PICO
P
Population
Cardiac metabolism
E
Exposure / Comparator
Exercise
The paper highlights the need to understand sex differences in exercise-induced cardiac metabolic remodeling and substrate utilization.
Cite This Study
Yang et al. (2022) conducted a review in Cardiac metabolism. Exercise was evaluated. Exercise induces dynamic changes in cardiac substrate metabolism, but the specific effects of acute and chronic exercise on metabolic pathway regulation remain unclear due to inconsistent findings.