Why the study?
What are the manifestations and risk factors of amsacrine-associated cardiotoxicity?
What are the manifestations and risk factors of amsacrine-associated cardiotoxicity?
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Amsacrine can cause serious cardiotoxicity including arrhythmias and heart failure, which does not appear to be dose-dependent but may be associated with hypokalemia.
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Weiss et al. (1986) studied this question.
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