Key result
Chemerin levels were significantly higher in pregnant women with gestational diabetes mellitus compared to normoglycemic controls (SMD 0.97).
Why the study?
Recent publications and meta-analyses investigating chemerin levels in gestational diabetes mellitus have remained inconclusive.
Are chemerin levels elevated in patients with gestational diabetes mellitus compared to normoglycemic pregnant controls?
Comparison
GDM cases vs normoglycemic pregnant controls
Design
Updated systematic review and meta-analysis
Authors
Loading...
May support chemerin as a GDM biomarker; leaves open prospective validation before clinical adoption.
Meta-Analysis (n=3,436)
Are chemerin levels elevated in patients with gestational diabetes mellitus compared to normoglycemic pregnant controls?
Standardized Mean Difference: 0.97 (95% CI 0.16–1.78)
p-value: p=0.020
Chemerin levels are significantly elevated in women with gestational diabetes mellitus, suggesting a potential role in its pathogenesis.
Aldharee et al. (2025) conducted a meta-analysis in Gestational Diabetes Mellitus (n=3,436). Chemerin levels vs. Normoglycemic pregnant controls was evaluated on Chemerin levels between GDM cases and normoglycemic controls (SMD 0.97, 95% CI 0.16-1.78, p=0.020). Chemerin levels were significantly higher in pregnant women with gestational diabetes mellitus compared to normoglycemic controls (SMD 0.97).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: