Key result
Carotid stenosis >60% and reduced cardiac output correlated with perioperative major cerebrovascular events (p<0.01), while prophylactic carotid endarterectomy decreased MCVE incidence (p<0.01).
Why the study?
Does prophylactic carotid endarterectomy or the 'pump off' technique reduce perioperative major cerebrovascular events in patients with carotid stenosis undergoing CABG?
Population
722 consecutive patients undergoing coronary artery bypass grafting who had carotid artery duplex scanning…
Comparison
Prophylactic carotid endarterectomy for patients… vs Standard cardiopulmonary bypass / no…
Design
Cohort
Follow-up
perioperative
Authors
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May support prophylactic CEA before CABG in select patients; hypothesis-generating and requires RCTs before changing practice.
Observational (n=722)
Does prophylactic carotid endarterectomy or the 'pump off' technique reduce perioperative major cerebrovascular events in patients with carotid stenosis undergoing CABG?
p-value: p=< 0.01
Prophylactic carotid endarterectomy and off-pump CABG may reduce the risk of perioperative major cerebrovascular events in patients with significant carotid stenosis undergoing coronary bypass surgery.
Bırıncıoğlu et al. (2010) conducted an observational in Coronary artery bypass grafting (CABG) (n=722). Carotid artery stenosis > 60% vs. Carotid stenosis ≤ 60% was evaluated on Perioperative major cerebrovascular events (MCVEs) (p=< 0.01). Carotid stenosis >60% and reduced cardiac output correlated with perioperative major cerebrovascular events (p<0.01), while prophylactic carotid endarterectomy decreased MCVE incidence (p<0.01).
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