Key result
A young woman with severe drug-induced heart failure following breast cancer treatment was successfully bridged to heart transplantation using a HeartMate II for 6 years.
Case Report (n=1)
Mechanical circulatory support can serve as an effective long-term bridge to transplantation for patients with cancer therapy-induced severe heart failure who are temporarily contraindicated for transplant.
Cardiotoxicity is a multifactorial problem, which has emerged with the improvement of cancer therapies and survival. Heart transplantation is relatively contraindicated in patients with breast cancer, until at least 5 years after complete remission. We present a case where a young woman who in 2001, at the age of 31, was diagnosed with breast cancer. She was considered cured, but 4 years later she suffered a relapse. During her second treatment, in 2006, she suffered from severe heart failure. She received a HeartMate II, as a long-term bridge to transplantation and 6 years later she was successfully transplanted. In this case report we discuss the use of mechanical circulatory support in cancer patients with drug-induced heart failure.
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Sundbom et al. (2014) conducted a case report in Breast cancer and cardiotoxicity with severe heart failure (n=1). HeartMate II was evaluated on Successful heart transplantation. A young woman with severe drug-induced heart failure following breast cancer treatment was successfully bridged to heart transplantation using a HeartMate II for 6 years.
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