Key result
In a community population of adults aged 40 and older, the prevalence of abnormal inter-ankle systolic blood pressure difference (≥10 mmHg) was 18.5%, with aging, obesity, and abnormal glucose metabolism identified as independent positive influencing factors.
Cross-Sectional (n=2,849)
Yes
Inter-ankle systolic blood pressure difference is prevalent in the community and is positively associated with aging, obesity, and abnormal glucose metabolism, suggesting it may be a useful screening index for peripheral artery disease.
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Should not yet change screening practices; supports prospective studies of inter-ankle BP difference for PAD detection.
AIM: The aim of this study was to investigate the prevalence of interankle systolic blood pressure difference (sIAND) and its influencing factors in community population. METHODS: This study included 2849 (65.1±9.4 y) subjects. Blood pressure (BPs) of four limbs was simultaneously measured with 4 electronic sphygmomanometers after 10 min rest in supine position. The difference of systolic BP (SBP) between two ankles was calculated as DETASBP. The criterion for abnormal sIAND was ≥10 mmHg of absolute DeltaSBP, in which the criterion for 1o sIAND was 10-19 mmHg and for 2o sIAND was ≥20 mmHg. Age, gender, smoking, hypertension, family histories of hypertension and diabetes were recorded. Fasting blood glucose and lipids, circumference of hip and waist, and body mass index (BMI) were measured. RESULTS: The SBP was higher in the right ankle than in the left ankle (158.9±21.8 vs 157.3±21.6 mmHg, P<0.05) and mean DeltaSBP was 6.08±6.26 mmHg. Similar difference was found in both genders. The prevalence of abnormal was 18.5%, in which, the prevalence 1o sIAND was 15.3% and that of 2o sIAND was 3.1%. Multivariate regression analysis showed that age, waist circumference and blood glucose level were the positive factors for DeltaSBP. The normal upper limit for DeltaSBP was 16.7 mmHg in this population, the prevalence of sIAND by≥16 mmHg was 5.8%. CONCLUSION: Aging, hypertension, obesity and abnormal glucose metabolism are positive factors for inter-ankle SBP difference.
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Zhang et al. (2013) conducted a cross-sectional in Inter-ankle systolic blood pressure difference (sIAND) (n=2,849). Risk factors (aging, hypertension, obesity, abnormal glucose metabolism) vs. Absence of risk factors was evaluated on Prevalence of abnormal inter-ankle systolic blood pressure difference (≥10 mmHg). In a community population of adults aged 40 and older, the prevalence of abnormal inter-ankle systolic blood pressure difference (≥10 mmHg) was 18.5%, with aging, obesity, and abnormal glucose metabolism identified as independent positive influencing factors.
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