Key result
Surgical resection of giant mediastinal teratoma resolves pseudo-heart failure symptoms in pregnancy.
Case Report (n=1)
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Extrinsic cardiopulmonary compression by a giant mediastinal teratoma can mimic preeclampsia-associated cardiopulmonary disease or peripartum cardiomyopathy in pregnant patients.
A woman in her early 20s at 30 weeks of gestation presented with elevated blood pressure, transaminitis, progressive dyspnoea, orthopnoea, exertional chest pain and peripheral oedema, raising concern for preeclampsia-associated cardiopulmonary disease or peripartum cardiomyopathy. Transthoracic echocardiography showed preserved left ventricular systolic function, normal left-sided filling pressures, right ventricular dilatation and an estimated right atrial pressure of 15 mmHg; N-terminal pro-brain natriuretic peptide was 57 pg/mL. Cross-sectional imaging revealed a large multi-cystic anterior mediastinal mass occupying the left hemithorax, displacing the heart and abutting/compressing major cardiopulmonary structures. Labour was induced at 34 weeks after clinical stabilisation. Three months postpartum, the patient re-presented with worsening dyspnoea and haemoptysis and underwent complete surgical resection. Pathology confirmed mature cystic teratoma and cardiopulmonary symptoms resolved after resection.
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VENTOSA et al. (2026) conducted a case report in Giant mediastinal teratoma mimicking heart failure in pregnancy (n=1). Surgical resection was evaluated on Resolution of cardiopulmonary symptoms. Complete surgical resection of a giant mediastinal teratoma resolved cardiopulmonary symptoms in a pregnant woman presenting with pseudo-heart failure.
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