Key result
Sildenafil treatment during puerperium resulted in a favorable clinical outcome in a patient with pregnancy-induced idiopathic pulmonary arterial hypertension.
Case Report (n=1)
Sildenafil treatment during puerperium showed a favorable outcome in a patient with pregnancy-induced idiopathic pulmonary arterial hypertension.
Hypothesis-generating for sildenafil in pregnancy-induced IPAH; larger studies needed before clinical adoption.
Idiopathic pulmonary arterial hypertension (IPAH) is characterized by a progressive increase in pulmonary vascular resistance, which may lead to right ventricular failure and death. Major cardiovascular and pulmonary alterations occur during pregnancy and therefore worsen or increase the complications of pulmonary arterial hypertension (PAH). A patient diagnosed with IPAH after a successful full-term pregnancy and cesarean section with epidural anesthesia is presented. The postoperative course was complicated by progressive dyspnea, and lower limb edema. The outcome of treatment with sildenafil during puerperium was favorable in this patient. The clinical course was complicated by an unexpected spontaneous pregnancy after primary infertility.
No takes yet. Share an insight, caveat, or question.
Taçoy et al. (2010) conducted a case report in Idiopathic pulmonary arterial hypertension (IPAH) (n=1). Sildenafil was evaluated on Clinical outcome. Sildenafil treatment during puerperium resulted in a favorable clinical outcome in a patient with pregnancy-induced idiopathic pulmonary arterial hypertension.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: