Estimation of Aortic Wall Sclerosis in Hypertension by Use of Carotid Pulse Tracing and Cine Magnetic Resonance

In order to evaluate aortic wall sclerosis in hypertension, the authors studied the following two parameters of carotid pulse tracing and ascending aortic wall distensibility by using cine magnetic resonance (MR) in 15 age- and sex-matched normal volunteers (NC) (mean age, fifty-four years old) and 15 hypertensive patients (HT) (mean age, fifty-four years old). As the parameters of carotid pulse tracing, they measured the interval from aortic second heart sound to dicrotic notch (A2-DN), and the height from dicrotic notch to top/total height of carotid pulse tracing (b/a ratio). Ascending aortic distensibility was calculated from the following formula: (max area - min area)/(min area x pulse pressure). A2-DN interval was lower in HT than in NC (18.4 +/- 7.9 vs 31.5 +/- 9.2 ms, P < 0.01). The b/a ratio was lower in HT than in NC (0.34 +/- 0.07 vs 0.44 +/- 0.09, P < 0.01). Ascending aortic distensibility was lower in HT than in NC (2.08 +/- 1.37 vs 7.26 +/- 2.51 x 10(-3) mmHg(-1), P < 0.01). In conclusion, ascending aortic wall sclerosis is advanced in hypertension. A2-DN interval and b/a ratio measured by carotid pulse tracing are useful indicators in evaluating the ascending aortic wall distensibility in hypertension.