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August 1, 1930Archives of Surgery

The Effect of Spinal Anesthesia on the Cardiac Output

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Why the study?

Does spinal anesthesia affect cardiac output and blood pressure in dogs?

Population

Dogs premedicated with morphine (10-15 mg/kg subcutaneously) or barbital (0.3 Gm/kg intravenously)

Design

Preclinical

Authors

JBJohn C. BurchSaint Thomas Health

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Implication

Does not support changes in human practice; leaves open translation of canine spinal anesthesia hemodynamics to clinical care.

Structured PICO

Does spinal anesthesia affect cardiac output and blood pressure in dogs?

P
Population
Dogs premedicated with morphine (10-15 mg/kg subcutaneously) or barbital (0.3 Gm/kg intravenously)
I
Intervention
Spinal anesthesia
O
Outcome
Cardiac output (determined by Fick principle) and arterial blood pressuresurrogate

This preclinical study investigates the physiologic effects of spinal anesthesia on cardiac output and blood pressure in a dog model.

Cite This Study

John C. Burch (1930) studied this question.

synapsesocial.com/papers/6a984a2ea6115088116c7cfbhttps://doi.org/10.1001/archsurg.1930.01150140147006
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1MECHANISM AND TREATMENT OF EXPERIMENTAL SHOCK1927 · 51 citations
  2. 2TRAUMA TO CENTRAL NERVOUS SYSTEM1929 · 6 citations