Why the study?
Does high spinal anesthesia impair the catecholamine release following cardiac arrest and CPR in a canine model?
Population
19 healthy, anesthetized, mongrel dogs
Comparison
High spinal anesthesia prior to induced cardiac… vs Sham-control prior to induced cardiac arrest and…
Design
Preclinical, Randomized
Follow-up
11 minutes of CPR
Authors
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Spinal anesthesia may blunt catecholamine response in arrest; leaves open effects on human CPR outcomes pending clinical studies.
Does high spinal anesthesia impair the catecholamine release following cardiac arrest and CPR in a canine model?
Spinal anesthesia abolishes the endogenous catecholamine release following cardiac arrest, suggesting catecholamine deficiency causes inadequate coronary perfusion pressure during CPR in this setting.
Rosenberg et al. (1998) studied this question.
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