Key result
Sutureless AVR reduced 30-day mortality compared to transcatheter AVR (OR 0.40; 95% CI 0.25-0.62; P<0.001), but showed no reduction versus conventional AVR.
Why the study?
Does sutureless AVR reduce 30-day mortality and complications compared to conventional AVR and TAVR in patients requiring aortic valve replacement?
Population
Patients requiring aortic valve replacement
Comparison
Sutureless aortic valve replacement (AVR) vs Conventional aortic valve replacement and…
Design
Meta-analysis
Follow-up
30-day
Authors
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Sutureless AVR may lower early mortality versus TAVR but not conventional surgery; extends comparative evidence while reinforcing surgery as benchmark.
Meta-Analysis
Does sutureless AVR reduce 30-day mortality and complications compared to conventional AVR and TAVR in patients requiring aortic valve replacement?
Odds Ratio: 0.4 (95% CI 0.25–0.62)
p-value: p=< 0.001
Sutureless AVR may reduce 30-day mortality and paravalvular leak compared to TAVR in low-to-intermediate risk patients, but offers no mortality benefit and higher pacemaker risk compared to conventional surgical AVR.
Qureshi et al. (2017) conducted a meta-analysis in Aortic valve replacement. Sutureless aortic valve replacement vs. Transcatheter AVR and conventional AVR was evaluated on 30-day mortality (OR 0.40, 95% CI 0.25-0.62, p=< 0.001). Sutureless AVR reduced 30-day mortality compared to transcatheter AVR (OR 0.40; 95% CI 0.25-0.62; P<0.001), but showed no reduction versus conventional AVR.
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