Key result
A 3-month physical exercise program significantly reduced circulating ANGPTL7 levels in obese subjects from 1249.05 pg/mL to 740.98 pg/mL.
Why the study?
Does physical exercise reduce ANGPTL7 levels in obese subjects?
Population
144 subjects, non-obese average age 40.44, obese average age 47.19. Excluded: morbidly obese, subjects…
Comparison
Three months of supervised physical exercise. vs Baseline levels and non-obese subjects.
Design
Cohort
Follow-up
3 months
Authors
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Exercise-associated ANGPTL7 reduction in obesity is hypothesis-generating; leaves open causal metabolic effects and need for RCTs.
Cohort (n=144)
No
Does physical exercise reduce ANGPTL7 levels in obese subjects?
Absolute Event Rate: 740.98% vs 1249.05%
p-value: p=0.007
Obesity is associated with increased ANGPTL7 levels in plasma and adipose tissue, which are significantly reduced following a 3-month physical exercise program, suggesting a potential role in lipid metabolism.
Abu‐Farha et al. (2017) conducted a cohort in Obesity (n=144). Physical exercise vs. Baseline (pre-exercise) was evaluated on Plasma ANGPTL7 level (p=0.007). A 3-month physical exercise program significantly reduced circulating ANGPTL7 levels in obese subjects from 1249.05 pg/mL to 740.98 pg/mL.
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