Key result
Circulating betatrophin levels were significantly elevated by 4.1 to 5.4 times in Japanese patients with type 1 and type 2 diabetes compared to healthy controls.
Why the study?
Are circulating betatrophin levels elevated in patients with type 1 and type 2 diabetes compared to healthy controls?
Population
76 Japanese subjects including 12 healthy controls, 34 patients with type 1 diabetes, and 30 patients with…
Design
Cross-sectional
Authors
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Elevated betatrophin in Japanese diabetes patients is hypothesis-generating; leaves open biomarker or therapeutic utility pending prospective validation.
Cross-Sectional (n=76)
No
Are circulating betatrophin levels elevated in patients with type 1 and type 2 diabetes compared to healthy controls?
Effect estimate: 4.1 to 5.4 times higher
p-value: p=<0.001
Circulating betatrophin is significantly elevated in Japanese patients with type 1 and type 2 diabetes and correlates with glucose and triglyceride levels.
Yamada et al. (2015) conducted a cross-sectional in Type 1 and Type 2 Diabetes (n=76). Diabetes mellitus vs. Healthy controls was evaluated on Circulating betatrophin levels (4.1 to 5.4 times higher, p=<0.001). Circulating betatrophin levels were significantly elevated by 4.1 to 5.4 times in Japanese patients with type 1 and type 2 diabetes compared to healthy controls.
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