Key result
Never-treated primary hypertension in young adults without LV hypertrophy was associated with lower LV global longitudinal strain (p=0.001) and higher twist (p=0.002) compared to normotensive controls.
Why the study?
Does never-treated primary hypertension alter early left ventricular function (global longitudinal strain and twist) in young adults without left ventricular hypertrophy compared to normotensive controls?
Population
80 young adults, comprising 40 patients with first diagnosed, never-treated primary hypertension and no left…
Comparison
Never-treated primary hypertension vs Sex- and age-matched normotensive controls
Design
Case-control
Authors
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May indicate early subclinical LV dysfunction in untreated young hypertension; leaves open utility of strain imaging for risk stratification.
Case-Control (n=80)
Does never-treated primary hypertension alter early left ventricular function (global longitudinal strain and twist) in young adults without left ventricular hypertrophy compared to normotensive controls?
p-value: p=0.001
Young adults with newly diagnosed, untreated hypertension exhibit early subclinical left ventricular dysfunction (reduced global longitudinal strain and increased twist) even before the development of left ventricular hypertrophy.
Shin et al. (2014) conducted a case-control in Primary hypertension (n=80). Never-treated primary hypertension vs. Normotensive controls was evaluated on Left ventricular global longitudinal strain (GLS) and twist (p=0.001). Never-treated primary hypertension in young adults without LV hypertrophy was associated with lower LV global longitudinal strain (p=0.001) and higher twist (p=0.002) compared to normotensive controls.
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