Key result
Severe H1N1 influenza A infection in critically ill patients was associated with right ventricular dilatation (50-80%) and systolic impairment (23%), but less left heart failure (17%).
Population
23 critically ill patients with laboratory-confirmed H1N1 influenza A infection and an available clinical…
Design
Cohort
Follow-up
28 days
Authors
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May support RV-focused monitoring in severe H1N1 sepsis; leaves open therapeutic implications pending prospective validation.
Observational (n=23)
Yes
Critically ill patients with severe H1N1 infection frequently exhibit right heart dilatation and failure, but have less left heart failure than expected compared to general septic populations.
Brown et al. (2010) conducted an observational in Severe H1N1 influenza A infection (n=23). Severe H1N1 influenza A infection was evaluated on Echocardiographic findings including right ventricular dilatation, right ventricular systolic impairment, and left ventricular systolic dysfunction. Severe H1N1 influenza A infection in critically ill patients was associated with right ventricular dilatation (50-80%) and systolic impairment (23%), but less left heart failure (17%).
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