Key result
A well plate microfluidic system was developed and successfully used to investigate dynamic platelet behavior in vitro under normal (0.1-20 dyn/cm2) and pathological (20-200 dyn/cm2) shear loads.
The well plate microfluidic system provides a high-throughput, low-volume method for studying platelet behavior under physiological and pathological shear stress in vitro.
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May enable high-throughput platelet studies under shear; leaves open clinical translation pending validation.
Conant et al. (2011) studied Vascular diseases and thrombus formation. Well plate microfluidic (WPM)-based system was evaluated on Dynamic platelet behavior under shear stress. A well plate microfluidic system was developed and successfully used to investigate dynamic platelet behavior in vitro under normal (0.1-20 dyn/cm2) and pathological (20-200 dyn/cm2) shear loads.
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