Why the study?
Does heparin therapy cause modifications in liver enzymes and platelet counts in patients with deep-vein thrombosis?
Does heparin therapy cause modifications in liver enzymes and platelet counts in patients with deep-vein thrombosis?
Heparin therapy, particularly when administered intravenously, is associated with a significant but reversible increase in liver transaminases without a concomitant fall in platelet counts.
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May warrant transaminase monitoring during heparin in DVT; leaves open whether route-specific effects require practice changes.
Lambert et al. (1986) studied this question.
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