Key result
An inter-arm systolic blood pressure difference of ≥15 mmHg was significantly associated with an increased risk of cardiovascular disease (OR 1.412) compared to a difference of <5 mmHg.
Why the study?
Inter-arm blood pressure difference has been advocated to be associated with cardiovascular mortality and morbidity, prompting investigation into its association with CVD.
Does an increased inter-arm blood pressure difference associate with a higher prevalence of cardiovascular disease in adults?
Cross-Sectional (n=10,126)
Does an increased inter-arm blood pressure difference associate with a higher prevalence of cardiovascular disease in adults?
Odds Ratio: 1.412 (95% CI 1.099–1.814)
p-value: p=0.007
An inter-arm systolic blood pressure difference of ≥15 mm Hg and a diastolic difference of ≥10 mm Hg are significantly associated with the presence of cardiovascular disease, supporting bilateral blood pressure measurement in primary care.
Inter-arm BP differences may support bilateral checks in adults; leaves open prospective prediction of incident CVD.
The inter-arm blood pressure difference has been advocated to be associated with cardiovascular mortality and morbidity. Our study aimed to investigate the association between Inter-arm systolic and diastolic blood pressure differences and Cardio Vascular Disease (CVD). A total of 10,126 participants aged 35–70 years old were enrolled in a prospective Fasa Persian Adult Cohort. In this cross-sectional study, the cutoff values for inter-arm blood pressure difference were less than 5, greater than 5, greater than 10, and greater than 15 mm Hg. Descriptive statistics and logistic regression were used to analyze the data. Based on the results the prevalence of ≥ 15 mmHg inter-arm systolic and diastole blood pressure difference (inter-arm SBPD and inter-arm DBPD) were 8.08% and 2.61%. The results of logistic regression analysis showed that inter-arm SBPD ≥ 15 and (OR<5/≥15 = 1.412; 95%CI = 1.099–1.814) and inter-arm DBPD ≥ 10 (OR<5/≥10 = 1.518; 95%CI = 1.238–1.862) affected the risk of CVD. The results showed that the differences in BP between the arms had a strong positive relationship with CVD. Therefore, inter-arm blood pressure could be considered a marker for the prevention and diagnosis of CVD for physicians.
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Sharafi et al. (2023) conducted a cross-sectional in Cardiovascular disease (n=10,126). Inter-arm systolic blood pressure difference ≥15 mmHg vs. Inter-arm systolic blood pressure difference <5 mmHg was evaluated on Cardiovascular disease (OR 1.412, 95% CI 1.099-1.814, p=0.007). An inter-arm systolic blood pressure difference of ≥15 mmHg was significantly associated with an increased risk of cardiovascular disease (OR 1.412) compared to a difference of <5 mmHg.
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