Key result
Exercise training improved neurovascular control more in hypertensive heart failure patients than idiopathic patients, with a greater reduction in MSNA frequency (-34% vs -15%, p=0.01).
Why the study?
Does the aetiology of heart failure influence the neurovascular and functional benefits of exercise training in patients with HFrEF?
Population
45 patients with heart failure, aged 40-70 years, divided into idiopathic, ischaemic, and hypertensive…
Comparison
Four months of exercise training vs Comparison among three HF aetiology groups…
Design
Cohort
Follow-up
4 months
Authors
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May indicate aetiology-specific neurovascular responses to exercise in HFrEF; hypothesis-generating and should not yet change practice.
Cohort (n=45)
Does the aetiology of heart failure influence the neurovascular and functional benefits of exercise training in patients with HFrEF?
Absolute Event Rate: -34% vs -15%
p-value: p=0.01
Exercise training improves neurovascular control more profoundly in hypertensive heart failure patients compared to idiopathic or ischaemic aetiologies, although functional capacity improvements are similar across groups.
Antunes‐Correa et al. (2016) conducted a cohort in Heart failure (n=45). Exercise training in hypertensive aetiology vs. Exercise training in idiopathic and ischaemic aetiologies was evaluated on Relative reduction in muscle sympathetic nerve activity (MSNA) frequency (p=0.01). Exercise training improved neurovascular control more in hypertensive heart failure patients than idiopathic patients, with a greater reduction in MSNA frequency (-34% vs -15%, p=0.01).
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