Key result
Elevated high-sensitivity C-reactive protein was an independent predictor of cardiac death and rehospitalization in patients with chronic heart failure (HR 3.81; 95% CI 2.14-9.35; p=0.024).
Why the study?
Does elevated hsCRP predict cardiac events in patients with chronic heart failure?
Population
128 patients with chronic heart failure (CHF) and 25 healthy control subjects
Design
Cohort
Follow-up
mean 378 +/- 26 days
Authors
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Does not yet warrant hsCRP-guided decisions in chronic HF; extends prognostic biomarker data but requires prospective validation.
Cohort (n=153)
Does elevated hsCRP predict cardiac events in patients with chronic heart failure?
Hazard Ratio: 3.81 (95% CI 2.14–9.35)
p-value: p=0.024
Elevated serum hsCRP is an independent predictor of cardiac death and heart failure rehospitalization in patients with chronic heart failure.
Xue et al. (2004) conducted a cohort in Chronic Heart Failure (n=153). High-sensitivity C-reactive protein (hsCRP) was evaluated on Cardiac events (cardiac death and rehospitalisation because of worsening heart failure) (HR 3.81, 95% CI 2.14-9.35, p=0.024). Elevated high-sensitivity C-reactive protein was an independent predictor of cardiac death and rehospitalization in patients with chronic heart failure (HR 3.81; 95% CI 2.14-9.35; p=0.024).
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