Key result
Percutaneous edge-to-edge tricuspid valve repair successfully improved symptoms and reduced tricuspid regurgitation to mild in a 27-year-old heart transplant recipient.
Why the study?
Surgical correction of severe tricuspid regurgitation carries high risk in post-heart transplant patients due to previous sternotomy and immunosuppression.
Does percutaneous edge-to-edge tricuspid valve repair improve symptoms and reduce regurgitation in orthotopic heart transplant recipients with severe tricuspid regurgitation?
Case Report (n=1)
Does percutaneous edge-to-edge tricuspid valve repair improve symptoms and reduce regurgitation in orthotopic heart transplant recipients with severe tricuspid regurgitation?
Percutaneous edge-to-edge tricuspid valve repair is a feasible and effective alternative to high-risk conventional surgery for severe tricuspid regurgitation in post-heart transplant patients.
May support percutaneous repair in post-transplant severe TR; hypothesis-generating, requires prospective confirmation before practice change.
Tricuspid valve regurgitation in orthotopic heart transplant recipients is common. Surgical corrections have been the mainstay of the treatment for diuretic-refractory heart failure due to severe tricuspid regurgitation. However, post-transplant patients inherently carry higher surgical risk owing to previous sternotomy and immunocompromised state. We report a case of successful percutaneous edge-to-edge tricuspid valve repair for severe tricuspid regurgitation after cardiac transplantation. A 27-year-old man with a history of idiopathic restrictive cardiomyopathy status after orthotopic heart transplant presented with severe right-sided heart failure symptoms. A transthoracic echocardiogram showed bi-atrial enlargement and moderate-to-severe tricuspid regurgitation, and an increase to the severe range with exercise. Percutaneous edge-to-edge tricuspid valve repair was performed. The patient's symptoms improved, and follow-up echocardiogram showed mild tricuspid regurgitation. Percutaneous tricuspid valve repair can be considered as an alternative option to conventional surgery for symptomatic severe tricuspid regurgitation in orthotopic heart transplant recipients with suitable anatomy.
No takes yet. Share an insight, caveat, or question.
Misumida et al. (2020) conducted a case report in Severe tricuspid regurgitation after cardiac transplantation (n=1). Percutaneous edge-to-edge tricuspid valve repair was evaluated on Symptom improvement and echocardiographic tricuspid regurgitation severity. Percutaneous edge-to-edge tricuspid valve repair successfully improved symptoms and reduced tricuspid regurgitation to mild in a 27-year-old heart transplant recipient.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: